Ⅰ. Microumedle Electrodes thiab lawv cov ntawv thov
Cov hluav taws xob microhedle yog microcale koob - zoo li cov khoom siv hluav taws xob mus sau electrophysiological lossis ua tiav hluav taws xob kev txhawb nqa. Lawv tau dav siv nyob rau hauv cov khoom siv hnav / immantable, neuroscience, thiab hlwb- khoos phis tawj interfaces. Lawv cov txiaj ntsig tseem ceeb yog lub peev xwm los txuas ntxiv hauv Vivo physiological xws li electromams thiab electromyograms thiab cov ntaub ntawv ncaj qha rau kev kuaj mob thiab kev kho mob.
Lub Utah electrode array, tsim los ntawm lub tsev kawm qib siab ntawm Utah, yog tus sawv cev thev naus laus zis hauv Microoneedle electrode arrays. Nws tshwj xeeb peb {- desensional koob- Piv txwv li cov qauv hluav taws xob daws teeb meem thiab rwb thaiv tsev zoo. Tom qab cog qoob loo, cov lus qhia hluav taws xob ua tsuas yog cov pab pawg neuronal ib puag ncig, thiab tuaj yeem sau cov hluav taws ntawm ib tus neuron. Nrog rau kev txhim kho ntawm Mems Technology, microhoneedle arrays tau pom cov kev txhim kho tseem ceeb hauv biocompatibility, ntev} lub sij hawm ruaj khov, thiab daws teeb meem.
Ⅱ. Electrophysiological teeb taw qhia kev daws teeb meem
Hauv cov biomedical teb, kev nrhiav thiab tsom xam ntawm electrophysiological cov cim tseem ceeb heev rau kev kuaj mob thiab kev kuaj mob. Txawm li cas los xij, cov cim no yog cov nyom thiab tsis muaj zog, ua kom tau txais kev sib tw tsis tu ncua. Tam sim no, muaj ob lub ntsiab kev daws teeb meem: cog thiab hnav.
Kev qhia daws cov kev daws teeb meem kev cuam tshuam nrog microcessedle electrode array mus rau tib neeg lub cev kom ua tiav qhov kev soj ntsuam ntawm Electrophysiological phiaj. Nws cov txiaj ntsig dag hauv siab Spatiotemporalal daws teeb meem thiab ruaj khov, raug ntes cov kev ua haujlwm ntawm tus neeg neurons. Txawm li cas los xij, nws tseem nthuav tawm cov kev sib tw xws li kev phais mob, tsis txaus ntev}} cov teeb meem ruaj khov, thiab cov teeb meem biocompatibility.
Cov kev daws teeb meem tseem ceeb ua ntej qhov yooj yim thiab xis nyob. Los ntawm embedding microneedle electrode arrays ntawm daim tawv nqaij saum npoo av lossis sab hauv khaub ncaws, cov neeg siv tau yooj yim saib xyuas electrophysiological phiaj. Qhov kev daws teeb meem tshem tawm qhov xav tau kev phais mob, txo kev pheej hmoo thiab kev txhim kho yooj yim ntawm kev siv thiab kev nplij siab. Txawm li cas los xij, nws tseem ntsib kev cov kev sib tw ua ke xws li kev cuam tshuam ntawm lub teeb liab thiab lub suab nrov suppression uas yuav tsum tau daws teeb meem.
Ⅲ. Cov ntawv thov ntawm microelecrododes hauv neuromedicine
Microelectrode cov cuab yeej siv tshuab, raws li cov cuab yeej tseem ceeb rau electrophysiological kev pom zoo, ua lub luag hauj lwm tseem ceeb hauv kev ua haujlwm thiab lub hlwb} lub computer cuam tshuam. Los ntawm impanting los yog hnav microelectrode arrays ntawm tib neeg lub cev, cov kws tshawb fawb tuaj yeem saib xyuas kev ua haujlwm ntawm lub sijhawm, thiab lwm yam kev kuaj mob hluav taws xob thiab kev kho mob ntawm kev kuaj mob neurological. Ib txhij, microelectrode array technology tau tseem coj tshiab tawg rau kev txhim kho ntawm lub hlwb thev naus laus zis, ua rau tib neeg tswj hwm cov cuab yeej sab nraud los ntawm kev xav.
Ⅳ. Polymer flexible microedle qhuav electrodes
Raws li cov polymers, yoog raws cov hluav taws xob qhuav yog cov khoom siv hluav taws xob neionalically screen neural hluav taws xob cov cim, muab cov cuab yeej tshiab rau kev tshawb fawb tshiab. Cov cuab yeej thev naus laus zis tsuas yog ua tau zoo ntawm kev ua tau zoo ntawm electrophysiological teeb meem tau txais tab sis kuj muaj cov kev kuaj mob tshiab rau kev kuaj mob thaum ntxov thiab kho kab mob nurological.